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Health Economics Wiki
Regulatory Conceptsevidence: highv1.0.0

Clinical Effectiveness

The extent to which a healthcare intervention produces beneficial health outcomes in real-world clinical practice.

Definition

Clinical effectiveness refers to the ability of an intervention to produce intended benefits under ordinary clinical conditions, as distinct from efficacy (performance in idealised trial conditions). In HTA, clinical effectiveness data form the basis for the economic model inputs. Sources include randomised controlled trials, systematic reviews, and meta-analyses.

Canonical Identity

Version
1.0.0
Published
4/26/2026
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