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Health Economics Wiki
Statistical Methodsevidence: highv1.0.0

Indirect Treatment Comparison

A method for comparing treatments not directly compared in randomised trials using a common comparator.

Definition

Indirect treatment comparison (ITC) allows estimation of relative treatment effects between interventions that have not been directly compared in head-to-head trials, using a shared common comparator (typically placebo or standard of care). The simplest form is the Bucher method. Network meta-analysis extends this to multiple comparators simultaneously.

Canonical Identity

Version
1.0.0
Published
4/26/2026
Structured Data
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