Statistical Methodsevidence: highv1.0.0
Subgroup Analysis
Analysis of outcomes within a defined subset of the trial or model population.
Definition
Subgroup analyses examine whether treatment effects differ across patient subgroups defined by baseline characteristics such as age, severity, biomarker status, or prior treatment. In economic evaluation, subgroup analyses may justify differential cost-effectiveness claims for specific patient populations. NICE requires pre-specification of subgroups and appropriate statistical correction for multiplicity.
Canonical Identity
- Authority
- https://www.darrinbaines.org
- Version
- 1.0.0
- Published
- 4/26/2026
- Structured Data
- View JSON-LD →